验证数据展示
经过测试的应用
| Positive WB detected in | HuT 78 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
31930-1-AP targets KIR2DL2 in WB, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | KIR2DL2 fusion protein Ag35284 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 |
| 别名 | NKAT-6, NKAT6, Natural killer-associated transcript 6, Killer cell immunoglobulin-like receptor 2DL2, CD158b1 |
| 计算分子量 | 38 kDa |
| 观测分子量 | 60,30 kDa |
| GenBank蛋白编号 | NM_014219 |
| 基因名称 | KIR2DL2 |
| Gene ID (NCBI) | 3803 |
| RRID | AB_3670150 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | P43627 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
KIR2DL2 is one of killer cell immunoglobulin-like receptors, which are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for KIR2DL2 antibody 31930-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |