KISS1R Polyclonal antibody
KISS1R Polyclonal Antibody for WB,ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse
Applications
WB,ELISA
Conjugate
Unconjugated
验证数据展示
经过测试的应用
| Positive WB detected in | Recombinant protein |
推荐稀释比
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
59009-1-Ig targets KISS1R in WB, ELISA applications and shows reactivity with human, mouse samples.
| Tested Applications | WB,ELISA Application Description |
| Tested Reactivity | human, mouse |
| Immunogen | Recombinant Protein 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | KISS1 receptor |
| Synonyms | AXOR12, G protein coupled receptor 54, GPR54, HOT7T175, Hypogonadotropin 1, KiSS 1 receptor, KiSS 1R, KISS1 receptor, KISS1R, Kisspeptins receptor, Metastin receptor |
| Calculated Molecular Weight | 398 aa, 43 kDa |
| GenBank Accession Number | BC141812 |
| Gene Symbol | KISS1R |
| Gene ID (NCBI) | 84634 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | Q969F8 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Receptor for metastin (kisspeptin-54, 13, 14, 10), C- terminally amidated peptides of KiSS-1. KiSS-1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some other carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins.