KLRG1 Polyclonal antibody
KLRG1 Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
WB, ELISA and More (1)
Conjugate
Unconjugated
验证数据展示
经过测试的应用
| Positive WB detected in | Jurkat cells, Raji cells, human peripheral blood leukocyte, NK-92 cells |
推荐稀释比
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:200-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| IF | See 1 publications below |
产品信息
10974-1-AP targets KLRG1 in WB, IF, ELISA applications and shows reactivity with human samples.
| Tested Applications | WB, ELISA Application Description |
| Cited Applications | IF |
| Tested Reactivity | human |
| Cited Reactivity | human |
| Immunogen | KLRG1 fusion protein Ag1407 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | killer cell lectin-like receptor subfamily G, member 1 |
| Synonyms | 2F1, CLEC15A, KLRG1, MAFA, MAFA 2F1, MAFA L, MAFA LIKE, MAFA like receptor, MAFAL |
| Calculated Molecular Weight | 22 kDa |
| Observed Molecular Weight | 60-70 kDa |
| GenBank Accession Number | BC012621 |
| Gene Symbol | KLRG1 |
| Gene ID (NCBI) | 10219 |
| RRID | AB_2234383 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q96E93 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
KLRG1 (killer cell lectin-like receptor subfamily G, member 1) is a C-type lectin inhibitory receptor that contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. KLRG1 is expressed by subsets of NK and T cells, existing both as a monomer and as a disulfide-linked homodimer (PMID: 10741410; 19604491). It is considered to be a cell differentiation marker for NK and T cells and is strongly induced by viral and other infections (PMID: 20373518). Through interactions with members of the cadherin family, KLRG1 plays an inhibitory role on NK- and T-cell function (PMID: 19009530; 20373518).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for KLRG1 antibody 10974-1-AP | Download protocol |
| IHC protocol for KLRG1 antibody 10974-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
J Neurol Morphological and molecular comparison of HIV-associated and sporadic inclusion body myositis |
