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KLRG1 Recombinant antibody, PBS Only

KLRG1 Uni-rAbTM Recombinant Antibody for IF/ICC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF/ICC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

242327A4

Cat no : 84785-5-PBS

Print datasheet

Synonyms

MAFA, Killer cell lectin-like receptor subfamily G member 1, ITIM-containing receptor MAFA-L, C-type lectin domain family 15 member A, CLEC15A

验证数据展示

  • IF Staining of Jurkat using 84785-5-RR (same clone as 84785-5-PBS)

    IF Staining of Jurkat using 84785-5-RR (same clone as 84785-5-PBS)

    Immunofluorescent analysis of (4% PFA) fixed Jurkat cells using KLRG1 antibody (84785-5-RR, Clone: 242327A4 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84785-5-PBS in a different storage buffer formulation.

  • IF Staining of NK-92 using 84785-5-RR (same clone as 84785-5-PBS)

    IF Staining of NK-92 using 84785-5-RR (same clone as 84785-5-PBS)

    Immunofluorescent analysis of (4% PFA) fixed NK-92 cells using KLRG1 antibody (84785-5-RR, Clone: 242327A4 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84785-5-PBS in a different storage buffer formulation.

产品信息

84785-5-PBS targets KLRG1 in IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications IF/ICC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen Recombinant protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name killer cell lectin-like receptor subfamily G, member 1
Synonyms MAFA, Killer cell lectin-like receptor subfamily G member 1, ITIM-containing receptor MAFA-L, C-type lectin domain family 15 member A, CLEC15A
Calculated Molecular Weight22 kDa
GenBank Accession NumberNM_005810.4
Gene Symbol KLRG1
Gene ID (NCBI) 10219
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ96E93-1
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

KLRG1 (killer cell lectin-like receptor subfamily G, member 1) is a C-type lectin inhibitory receptor that contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. KLRG1 is expressed by subsets of NK and T cells, existing both as a monomer and as a disulfide-linked homodimer (PMID: 10741410; 19604491). It is considered to be a cell differentiation marker for NK and T cells and is strongly induced by viral and other infections (PMID: 20373518). Through interactions with members of the cadherin family, KLRG1 plays an inhibitory role on NK- and T-cell function (PMID: 19009530; 20373518).