KMO Monoclonal antibody
KMO Monoclonal Antibody for WB, ELISA
Host / Isotype
Mouse / IgG1
Reactivity
human and More (1)
Applications
WB, ELISA and More (2)
Conjugate
Unconjugated
CloneNo.
2D2F2
验证数据展示
经过测试的应用
| Positive WB detected in | PC-3 cells, SKOV-3 cells |
推荐稀释比
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:5000-1:50000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
60029-1-Ig targets KMO in WB, IF, IHC, ELISA applications and shows reactivity with human samples.
| Tested Applications | WB, ELISA Application Description |
| Cited Applications | WB, IF, IHC |
| Tested Reactivity | human |
| Cited Reactivity | human, mouse |
| Immunogen | KMO fusion protein Ag1109 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| Synonyms | KMO, Kynurenine 3 hydroxylase, Kynurenine 3 monooxygenase |
| Calculated Molecular Weight | 486 aa, 56 kDa |
| Observed Molecular Weight | 56 kDa |
| GenBank Accession Number | BC005297 |
| Gene Symbol | KMO |
| Gene ID (NCBI) | 8564 |
| RRID | AB_2133396 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | O15229 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
KMO(Kynurenine 3-monooxygenase) is a membrane protein located on the outer membrane of mitochondria. Tissue distribution studies have revealed that, in rats, highest enzyme activity is found in kidney and liver, with brain having the least activity in comparison to peripheral organs(PMID: 9237672).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for KMO antibody 60029-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Neuro Oncol Molecular imaging correlates of tryptophan metabolism via the kynurenine pathway in human meningiomas. | ||
Oncol Lett Viability of diffuse large B-cell lymphoma cells is regulated by kynurenine 3-monooxygenase activity | ||
Hum Mol Genet Retention of stress susceptibility in the mdx mouse model of Duchenne muscular dystrophy after PGC-1α overexpression or ablation of IDO1 or CD38 |