验证数据展示
产品信息
83812-1-PBS targets KMO in WB, IHC, FC (Intra), ELISA applications and shows reactivity with human, mouse samples.
Tested Applications | WB, IHC, FC (Intra), ELISA Application Description |
Tested Reactivity | human, mouse |
Immunogen | KMO fusion protein Ag35029 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
Synonyms | Kynurenine 3-monooxygenase, Kynurenine 3-hydroxylase, Kynurenine 3 monooxygenase, Kynurenine 3 hydroxylase, EC:1.14.13.9 |
Calculated Molecular Weight | 486 aa, 56 kDa |
Observed Molecular Weight | 52-56 kDa |
GenBank Accession Number | BC005297 |
Gene Symbol | KMO |
Gene ID (NCBI) | 8564 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | O15229 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
KMO(Kynurenine 3-monooxygenase) is an NADPH-dependent flavin monooxygenase, catalysing the hydroxylation of the L-kynurenine to form L-3-hydroxykynurenine. KMO is a membrane protein located on the outer membrane of mitochondria. Tissue distribution studies have revealed that, in rats, highest enzyme activity is found in kidney and liver, with brain having the least activity in comparison to peripheral organs(PMID: 9237672).