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KS176

KS176是选择性高活性乳腺癌耐药蛋白多药转运通道抑制剂，在Pheo A 和Hoechst 检测中，IC50值分别为0.59和1.39 μM。

CAS号

1253452-78-6

分子式

C22H19N3O5

主要靶点

Potassium Channel|BCRP

仅限科研使用

Cat No : CM03146

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Synonyms

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  • CAS No.: 1253452-78-6

    KS176
    CAS#: 1253452-78-6

产品信息

KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter, showing no inhibitory activity against P-gp or MRP1.

CAS号 1253452-78-6
分子式 C22H19N3O5
主要靶点 Potassium Channel|BCRP
主要通路 离子通道
分子量 405.41
纯度 99.78%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名

靶点活性

BCRP(Pheo A):0.59 μM

溶解度

DMSO:35 mg/mL

参考文献

1.Pick A, et al. Specific inhibitors of the breast cancer resistance protein (BCRP). ChemMedChem. 2010 Sep 3;5(9):1498-505.

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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