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Species Reactivity
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验证数据展示

  • IHC staining of human lymphoma using 18131-1-AP (same clone as 18131-1-PBS)

    IHC staining of human lymphoma using 18131-1-AP (same clone as 18131-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lymphoma using 18131-1-AP (FERMT3 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 18131-1-PBS in a different storage buffer formulation.

  • IF Staining of HeLa using 18131-1-AP (same clone as 18131-1-PBS)

    IF Staining of HeLa using 18131-1-AP (same clone as 18131-1-PBS)

    Immunofluorescent analysis of HeLa cells using 18131-1-AP (FERMT3 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 18131-1-PBS in a different storage buffer formulation.

  • WB analysis using 18131-1-AP (same clone as 18131-1-PBS)

    WB analysis using 18131-1-AP (same clone as 18131-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 18131-1-AP (Kindlin 3 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18131-1-PBS in a different storage buffer formulation.

  • WB analysis using 18131-1-AP (same clone as 18131-1-PBS)

    WB analysis using 18131-1-AP (same clone as 18131-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 18131-1-AP (Kindlin 3 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18131-1-PBS in a different storage buffer formulation.

Kindlin 3 Polyclonal antibody, PBS Only

Kindlin 3 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 18131-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

18131-1-PBS targets Kindlin 3 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 Kindlin 3 fusion protein Ag12713 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 fermitin family homolog 3 (Drosophila)
别名
计算分子量 76 kDa
观测分子量 72-76 kDa
GenBank蛋白编号BC004347
基因名称 Kindlin 3/FERMT3
Gene ID (NCBI) 83706
RRIDAB_2103056
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ86UX7
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Kindlin-3 (FERMT-3) is known to be central in hemostasis and thrombosis control and its deficiency disrupts platelet aggregation and causes Leukocyte Adhesion Deficiency disease. Point mutations in the kindlin-3 gene have been identified in humans with a rare inherited Integrin Activation efficiency Disease (IADD), also designated as Leukocyte Adhesion Deficiency syndrome (LAD-III or LADI variant). Kindlin-3 expression is restricted to cells of hematopoietic origin.