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验证数据展示

  • WB analysis using 15707-1-AP (same clone as 15707-1-PBS)

    WB analysis using 15707-1-AP (same clone as 15707-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 15707-1-AP (L2HGDH antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15707-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver cancer using 15707-1-AP (same clone as 15707-1-PBS)

    IHC staining of human liver cancer using 15707-1-AP (same clone as 15707-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 15707-1-AP (L2HGDH antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15707-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver cancer using 15707-1-AP (same clone as 15707-1-PBS)

    IHC staining of human liver cancer using 15707-1-AP (same clone as 15707-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 15707-1-AP (L2HGDH antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15707-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

L2HGDH Polyclonal antibody, PBS Only

L2HGDH Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 15707-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

15707-1-PBS targets L2HGDH in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 L2HGDH fusion protein Ag8382 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 L-2-hydroxyglutarate dehydrogenase
别名
计算分子量463aa,50 kDa; 441aa,49 kDa
观测分子量 45 kDa
GenBank蛋白编号BC006117
基因名称 L2HGDH
Gene ID (NCBI) 79944
RRIDAB_2133202
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9H9P8
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

L2HGDH(L-2-hydroxyglutarate dehydrogenase, mitochondrial) is also named as duranin, C14orf160 and belongs to the L2HGDH family. The putative L2HGDH is predicted to be targeted to the mitochondria where its mitochondrial targeting sequence is presumably removed(PMID:16005139). Defects in L2HGDH are the cause of L-2-hydroxyglutaric aciduria (L2HGA). It has 2 isoforms produced by alternative splicing with the molecular weight of 50 kDa and 48 kDa. L2HGDH also can be detected as ~45kD due to the 51aa transit peptide cleaved.