L3MBTL2 Polyclonal antibody

L3MBTL2 Polyclonal Antibody for WB, ELISA
Cat No. 24435-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, ELISA

L(3)mbt-like protein 2, L(3)mbt like protein 2, l(3)mbt like 2 (Drosophila), H-l(3)mbt-like protein 2, H l(3)mbt like protein 2

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inU2OS cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

24435-1-AP targets L3MBTL2 in WB, ELISA applications and shows reactivity with human samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human
免疫原 L3MBTL2 fusion protein Ag19571 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 l(3)mbt-like 2 (Drosophila)
别名 L(3)mbt-like protein 2, L(3)mbt like protein 2, l(3)mbt like 2 (Drosophila), H-l(3)mbt-like protein 2, H l(3)mbt like protein 2
计算分子量 705 aa, 79 kDa
观测分子量95-100 kDa
GenBank蛋白编号BC017191
基因名称 L3MBTL2
Gene ID (NCBI) 83746
RRIDAB_3085733
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ969R5
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

L3MBTL2 (Lethal (3) malignant brain tumor like 2) is a member of the MBT-domain proteins, which are involved in transcriptional repression and implicated in chromatin compaction. L3MBTL2 was most highly expressed in pachytene spermatocytes within the testis (PMID: 30760872).In addition, mutations in L3MBTL2 are prevalent in various cancers including leukemia, a disease characterized by alterations in multiple DNA repair proteins (PMID: 29581593).

实验方案

Product Specific Protocols
WB protocol for L3MBTL2 antibody 24435-1-APDownload protocol
Standard Protocols
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