验证数据展示
发表文章中的应用
| IHC | See 4 publications below |
| IF | See 7 publications below |
产品信息
10397-1-AP targets LAMP2 in IF, IHC, ELISA applications and shows reactivity with human samples.
| 经测试应用 | ELISA Application Description |
| 文献引用应用 | IF, IHC |
| 经测试反应性 | human |
| 文献引用反应性 | human, mouse, rat |
| 免疫原 | LAMP2 fusion protein Ag0595 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | lysosomal-associated membrane protein 2 |
| 别名 | CD107b, LAMP 2, LAMP2, LAMPB, LGP110 |
| 计算分子量 | 45 kDa |
| GenBank蛋白编号 | BC002965 |
| 基因名称 | LAMP2 |
| Gene ID (NCBI) | 3920 |
| ENSEMBL Gene ID | ENSG00000005893 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P13473 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Lysosomal-associated membrane protein 2 (LAMP2, synonyms: LAMPB, CD107b) is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. LAMP2 may plays a role in tumor cell metastasis. It may also functions in the protection, maintenance, and adhesion of the lysosome. Prior to posttranslational modification, LAMP2 is a ~45 kDa polypeptide. Mature, functional LAMP2 is extensively glycosylated with a variety of different N linked and O linked oligosaccharides, with apparent molecular weight ranging from 45-130 kDa.
发表文章
| Species | Application | Title |
|---|---|---|
Oxid Med Cell Longev The Inhibition of miR-873 Provides Therapeutic Benefit in a Lipopolysaccharide-Induced Neuroinflammatory Model of Parkinson's Disease. | ||
Cell Death Dis Dual induction of apoptotic and autophagic cell death by targeting survivin in head neck squamous cell carcinoma. | ||
Acta Neuropathol Commun Novel antibodies reveal presynaptic localization of C9orf72 protein and reduced protein levels in C9orf72 mutation carriers. | ||
Sci Rep Basal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD88. | ||
Front Pharmacol Glutamine Availability Regulates the Development of Aging Mediated by mTOR Signaling and Autophagy. |
