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LASS2 Recombinant antibody, PBS Only

LASS2 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241898E11

Cat no : 84514-4-PBS

Print datasheet

Synonyms

Sphingosine N-acyltransferase CERS2, EC:2.3.1.297, EC:2.3.1.24, CerS2, Ceramide synthase 2

验证数据展示

  • WB analysis using 84514-4-RR (same clone as 84514-4-PBS)

    WB analysis using 84514-4-RR (same clone as 84514-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84514-4-RR (LASS2 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84514-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84514-4-RR

    Affinity and Kinetic Characterization of 84514-4-RR

    Biolayer interferometry (BLl) kinetic assays of 84514-4-RR against Human LASS2 were performed. The affinity constant is 0.549 nM.

产品信息

84514-4-PBS targets LASS2 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human
Immunogen LASS2 fusion protein Ag14151 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name LAG1 homolog, ceramide synthase 2
Synonyms Sphingosine N-acyltransferase CERS2, EC:2.3.1.297, EC:2.3.1.24, CerS2, Ceramide synthase 2
Calculated Molecular Weight 380 aa, 45 kDa
Observed Molecular Weight40 kDa
GenBank Accession NumberBC010032
Gene Symbol LASS2
Gene ID (NCBI) 29956
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ96G23
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

LASS2, also known as TMSG1, is a novel suppressor of human cancer metastasis. As one member of LASS family, including LASS1-6, LASS2 mRNA is at the highest level of all LASS members, and has the broadest tissue distribution, particularly abundant in the liver, kidney and brain in mice. The biological roles of LASS2 include protection from aging , hepatic INS resistance, and hepatocellular carcinoma (HCC) progression. LASS2 has been correlated with the degree of invasion and recurrence of carcinomas of the prostate, liver, breast and bladder.