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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 30174-1-AP (same clone as 30174-1-PBS)

    WB analysis using 30174-1-AP (same clone as 30174-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30174-1-AP (LATS1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30174-1-PBS in a different storage buffer formulation.

  • WB analysis using 30174-1-AP (same clone as 30174-1-PBS)

    WB analysis using 30174-1-AP (same clone as 30174-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30174-1-AP (LATS1 antibody) at dilution of 1:7000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30174-1-PBS in a different storage buffer formulation.

LATS1 Polyclonal antibody, PBS Only

LATS1 Polyclonal Antibody for WB, Indirect ELISA
Cat No. 30174-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

30174-1-PBS targets LATS1 in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 LATS1 fusion protein Ag32879 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 LATS, large tumor suppressor, homolog 1 (Drosophila)
别名
观测分子量130 kDa
GenBank蛋白编号BC002767
基因名称 LATS1
Gene ID (NCBI) 9113
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDO95835
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

LATS1(Large tumor suppressor homolog 1) is also named as WARTS and belongs to the AGC Ser/Thr protein kinase family. The gene encodes a highly conserved (from fly to human) protein kinase that plays a crucial role in the prevention of tumor formation by controlling the progression of mitosis. The expression of both long(170 kDa) and short lats1 isoforms(120 kDa) in vertebrate retinal cells raises the possibility that these lats1 proteins may act as negative key regulators of the cell cycle each of them performing a unique role (PMID:15777619). In mammalian cells, LATS1 was phosphorylated in a cell cycle-dependent manner and complexed with CDC2 in early mitosis (PMID:9988268). LATS1 also can be detected as 120 kDa and 140-150 kDa, and play a key role in the regulation of Hippo pathway (PMID: 27940445).