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LC3-mHTT-IN-AN2

LC3-mHTT-IN-AN2 (5,7-Dihydroxy-4-phenylcoumarin) 是一种 mHTT-LC3 接头化合物，可与突变亨廷顿蛋白(mHTT) 和 LC3B 相互作用。 它将 mHTT 靶向自噬体以等位基因选择性方式降低培养的亨廷顿病小鼠神经元中的 mHTT 水平。它存在于西番莲植物中，具有抗菌活性。

CAS号

7758-73-8

分子式

C15H10O4

主要靶点

Autophagy|ATTECs|Antibacterial

仅限科研使用

Cat No : CM07826

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Synonyms

5,7-二羟基-4-苯基香豆素|5,7-Dihydroxy-4-phenylcoumarin

验证数据展示

  • CAS No.: 7758-73-8

    LC3-mHTT-IN-AN2
    CAS#: 7758-73-8

产品信息

5,7-dihydroxy-4-phenyl coumarin is found in the plant Passiflora serratodigitata with the antibacterial activity.

CAS号 7758-73-8
分子式 C15H10O4
主要靶点 Autophagy|ATTECs|Antibacterial
主要通路 微生物学|PROTAC|自噬
分子量 254.2375
纯度 91.45%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 5,7-二羟基-4-苯基香豆素|5,7-Dihydroxy-4-phenylcoumarin

溶解度

DMSO:10 mM

参考文献

1.Veselinović, JB, et al. Antibacterial potential of selected 4-phenyl hydroxycoumarins: integrated in vitro and molecular docking studies. Med Chem Res, 2015, 24(4):1626-1634.

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