验证数据展示
经过测试的应用
Positive WB detected in | human placenta tissue |
推荐稀释比
应用 | 推荐稀释比 |
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Western Blot (WB) | WB : 1:500-1:1000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
17823-1-AP targets LGALS13 in WB, ELISA applications and shows reactivity with human samples.
经测试应用 | WB, ELISA Application Description |
经测试反应性 | human |
免疫原 | LGALS13 fusion protein Ag12192 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | lectin, galactoside-binding, soluble, 13 |
别名 | Galectin-13, Galectin 13, Galactoside-binding soluble lectin 13, Gal-13, GAL13 |
计算分子量 | 139 aa, 16 kDa |
观测分子量 | 16 kDa |
GenBank蛋白编号 | BC066304 |
基因名称 | LGALS13 |
Gene ID (NCBI) | 29124 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q9UHV8 |
储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Galectins are glycan-binding proteins that regulate innate and adaptive immune responses, and some confer maternal-fetal immune tolerance in eutherian mammals. Three of the five human cluster galectins are solely expressed in the placenta, where they may confer additional immunoregulatory functions to enable deep placentation (PMID: 25191322). One of these is galactoside-binding soluble lectin 13 (LGALS13, also known as Galectin-13 and PP13), which has a high affinity for the sugar residues of glycoproteins. PP13 is implicated in placentation and is involved in inflammation and immune defense required for trophoblast invasion during uterine artery remodeling in early pregnancy (PMID: 19497882; 10527825; 21596368; 26018511).
实验方案
Product Specific Protocols | |
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WB protocol for LGALS13 antibody 17823-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |