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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis of human blood using 60066-1-Ig (same clone as 60066-1-PBS)

    WB analysis of human blood using 60066-1-Ig (same clone as 60066-1-PBS)

    human blood were subjected to SDS PAGE followed by western blot with 60066-1-Ig (LGALS3BP Antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60066-1-PBS in a different storage buffer formulation.

  • IF Staining of A431 using 60066-1-Ig (same clone as 60066-1-PBS)

    IF Staining of A431 using 60066-1-Ig (same clone as 60066-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed A431 cells using LGALS3BP antibody (60066-1-Ig, Clone: 2D8E11 ) at dilution of 1:800 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 60066-1-PBS in a different storage buffer formulation.

  • IP experiment of human plasma using 60066-1-Ig (same clone as 60066-1-PBS)

    IP experiment of human plasma using 60066-1-Ig (same clone as 60066-1-PBS)

    IP result of anti-LGALS3BP (IP:60066-1-Ig, 5ug; Detection:60066-1-Ig 1:1000) with human plasma lysate 4000ug. This data was developed using the same antibody clone with 60066-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 60066-1-Ig (same clone as 60066-1-PBS)

    IHC staining of human breast cancer using 60066-1-Ig (same clone as 60066-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 60066-1-Ig (LGALS3BP Antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60066-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 60066-1-Ig (same clone as 60066-1-PBS)

    IHC staining of human breast cancer using 60066-1-Ig (same clone as 60066-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 60066-1-Ig (LGALS3BP Antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60066-1-PBS in a different storage buffer formulation.

LGALS3BP Monoclonal antibody, PBS Only

LGALS3BP Monoclonal Antibody for WB, IHC, IF/ICC, IP, ELISA
Cat No. 60066-1-PBS

产品说明书

CloneNo. 2D8E11

宿主/亚型

Mouse / IgG2b

种属反应性

human

应用

WB, IHC, IF/ICC, IP, ELISA

别名

Lectin galactoside-binding soluble 3-binding protein, Galectin-3-binding protein, Galectin 3 binding protein, BTBD17B, 90K

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

60066-1-PBS targets LGALS3BP in WB, IHC, IF/ICC, IP, ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, IF/ICC, IP, ELISA Application Description
经测试反应性 human
免疫原 LGALS3BP fusion protein Ag0294 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 lectin, galactoside-binding, soluble, 3 binding protein
别名 Lectin galactoside-binding soluble 3-binding protein, Galectin-3-binding protein, Galectin 3 binding protein, BTBD17B, 90K
计算分子量 585 aa, 65 kDa
观测分子量 65-90 kDa
GenBank蛋白编号BC002403
基因名称 LGALS3BP
Gene ID (NCBI) 3959
RRIDAB_2265800
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ08380
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-3-binding protein (LGALS3BP, also known as 90K or Mac-2 BP) is a secreted glycoprotein which binds galectin-3, galectin-1, beta1 integrins, collagens and fibronectin (PMID: 8034587; 8024581; 11146440; 9501082). It has been implicated in tumor metastatic processes, as well as in other cell adhesion and immune functions. Levels of LGALS3BP have been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV) (PMID: 7698018). Western analysis suggests that LGALS3BP is found in breast milk, semen, saliva, urine, and tears, in addition to serum (PMID: 8390986 ). LGALS3BP has a predicted mass of ∼65 kDa. It is heavily glycosylated and shows an apparent molecular weight of 90 kDa on SDS-PAGE.