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LINGO1 Polyclonal antibody, PBS Only

LINGO1 Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 19097-1-PBS

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Synonyms

验证数据展示

  • WB analysis of mouse brain using 19097-1-AP (same clone as 19097-1-PBS)

    WB analysis of mouse brain using 19097-1-AP (same clone as 19097-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 19097-1-AP (LINGO1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19097-1-PBS in a different storage buffer formulation.

产品信息

19097-1-PBS targets LINGO1 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen LINGO1 fusion protein Ag13553 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name leucine rich repeat and Ig domain containing 1
Synonyms
Calculated Molecular Weight 70 kDa
Observed Molecular Weight 83 kDa
GenBank Accession NumberBC011057
Gene Symbol LINGO1
Gene ID (NCBI) 84894
RRIDAB_10638484
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ96FE5
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

LINGO-1 is a transmembrane receptor that contains 12 leucine-rich repeats and an immunoglobulin domain. It is expressed primarily in the central nervous system. LINGO-1 binds Nogo-66 receptor (NgR) and p75 and that is a functional component of the NgR/p75 signaling complex (PMID: 14966521). This protein has a calculated molecular weight of 70 kDa and migrates at higher molecular weight due to glycosylation (PMID: 21872576; 25257685; 18326721).