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LNX1 Polyclonal antibody

LNX1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Cat No : 13124-1-AP

Print datasheet

Synonyms

ligand of numb protein X 1, LNX, LNX1, MPDZ, Numb binding protein 1, PDZRN2

验证数据展示

  • WB analysis of mouse testis using 13124-1-AP

    WB analysis of mouse testis using 13124-1-AP

    mouse testis tissue were subjected to SDS PAGE followed by western blot with 13124-1-AP (LNX1 antibody) at dilution of 1:70 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inmouse testis tissue, mouse kidney tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2400
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

13124-1-AP targets LNX1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen LNX1 fusion protein Ag3823 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name ligand of numb-protein X 1
Synonyms ligand of numb protein X 1, LNX, LNX1, MPDZ, Numb binding protein 1, PDZRN2
Calculated Molecular Weight 728 aa, 81 kDa
Observed Molecular Weight 70 kDa
GenBank Accession NumberBC022983
Gene Symbol LNX1
Gene ID (NCBI) 84708
RRIDAB_2136987
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ8TBB1
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

LNX1 (Ligand of Numb, protein X 1) was originally identified as a binding partner of the cell-fate determinant Numb and was reported to be involved in ubiquitylation and degradation of Numb. LNX1 contains four PDZ domains and may function as a scaffold for a multi-protein complex. LNX1 has two splicing variants, LNX1p70 and LNX1p80. LNX1p70 has the N-terminal Numb binding region and four PDZ domains, whereas LNX1p80 has an additional RING-finger domain at the N-terminus followed by a Numb-binding region and four PDZ domains. This antibody can detect both LNX1p70 and LNX1p80, around 70-80 kDa and 80-100 kDa, respectively.

实验方案

Product Specific Protocols
WB protocol for LNX1 antibody 13124-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols