验证数据展示
产品信息
55497-1-AP targets LRRK2 in ELISA applications and shows reactivity with human samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | leucine-rich repeat kinase 2 |
| 别名 | PARK8, Leucine-rich repeat serine/threonine-protein kinase 2, leucine rich repeat kinase 2, EC:2.7.11.1, Dardarin |
| 计算分子量 | 286 kDa |
| GenBank蛋白编号 | NM_198578 |
| 基因名称 | LRRK2 |
| Gene ID (NCBI) | 120892 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q5S007 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
LRRK2, also termed Dardarin and PARK8, belongs to the protein kinase superfamily and TKL Ser/Thr protein kinase family. It is a protein kinase whose role is not yet known. LRRK2 may play a role in the phosphorylation of proteins central to Parkinson disease. It may also have GTPase activity (PMID:16352719). Defects in LRRK2 are the causes of Parkinson disease type 8 (PARK8). This antibody is specific to LRRK2.