LSAMP Polyclonal antibody

LSAMP Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 13600-1-AP

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Synonyms

IgLON family member 3, IGLON3, LAMP, LSAMP



经过测试的应用

Positive WB detected inhuman brain tissue, mouse brain tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

13600-1-AP targets LSAMP in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen LSAMP fusion protein Ag4542 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name limbic system-associated membrane protein
Synonyms IgLON family member 3, IGLON3, LAMP, LSAMP
Calculated Molecular Weight 338 aa, 37 kDa
Observed Molecular Weight 64-68 kDa
GenBank Accession NumberBC033803
Gene Symbol LSAMP
Gene ID (NCBI) 4045
RRIDAB_10597712
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ13449
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

LSAMP, also known as LAMP, is a 64-68 kDa heavily glycosylated neural cell adhesion molecule expressed on the neuronal dendrites and somata (PMID: 1688937; 8666243). LSAMP is a member of the IgLON family. The amino acid sequence of LSAMP is highly conserved among species. Human LSAMP shares 99% amino acid sequence identity with rodent LSAMP. The impact of LSAMP protein on neurite outgrowth and neuronal connectivity has been established in a wide spectrum of psychiatric disorders in humans (PMID: 26136648). In mice, lack of LSAMP protein seemingly leads to a deterioration in the ability to adapt to novel stressful environments and stimuli (PMID: 22155487).

实验方案

Product Specific Protocols
WB protocol for LSAMP antibody 13600-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols