LSR Polyclonal antibody

LSR Polyclonal Antibody for WB, IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, rat, mouse

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

Cat no : 18216-1-AP

Print datasheet

Synonyms

ILDR3, LISCH, LISCH7, LSR



经过测试的应用

Positive WB detected inHT-29 cells, HepG2 cells, mouse liver tissue, rat liver tissue
Positive IHC detected inmouse stomach tissue, mouse liver tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Immunohistochemistry (IHC)IHC : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

WBSee 1 publications below

产品信息

18216-1-AP targets LSR in WB, IHC, ELISA applications and shows reactivity with human, rat, mouse samples.

Tested Applications WB, IHC, ELISA Application Description
Cited ApplicationsWB
Tested Reactivity human, rat, mouse
Cited Reactivitymouse
Immunogen LSR fusion protein Ag12961 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name lipolysis stimulated lipoprotein receptor
Synonyms ILDR3, LISCH, LISCH7, LSR
Calculated Molecular Weight 71 kDa
Observed Molecular Weight 60-70 kDa, 56 kDa
GenBank Accession NumberBC004381
Gene Symbol LSR
Gene ID (NCBI) 51599
RRIDAB_2250137
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ86X29
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

LSR (lipolysis stimulated lipoprotein receptor) is a lipoprotein receptor primarily expressed in the liver and activated by free fatty acids (PMID: 10224102). This remnant receptor binds both apoB- and apoE-containing lipoproteins and displays greatest affinity for TG-rich lipoproteins. Distribution of LSR causes embryonic lethality in mice, indicating that the expression of LSR is critical for liver and embryonic development (PMID: 15265030). Investigations show that LSR is a multimer consisting of α subunit (68 kDa) and β subunit (56 kDa) associated through disulfide bridges (PMID: 10224102; 19188430; 18644789).

实验方案

Product Specific Protocols
WB protocol for LSR antibody 18216-1-APDownload protocol
IHC protocol for LSR antibody 18216-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle

Biosens Bioelectron

A multiple mixed TiO2 mesocrystal junction based PEC-colorimetric immunoassay for specific recognition of lipolysis stimulated lipoprotein receptor.

Authors - Yanjie Chen
mouseWB

J Hazard Mater

Multi-omics analyses reveal the mechanisms of Arsenic-induced male reproductive toxicity in mice.

Authors - Zijun Peng