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CD73-IN-3

CD73-IN-3 (LY-3475070) 是一种有效的选择性 CD73 抑制剂，IC50 为 28 nM，具有癌症的研究潜力。详细信息来源于专利 WO2019168744 A1 中的例 2 。

CAS号

2375815-63-5

分子式

C15H18N4O2

主要靶点

CD73

仅限科研使用

Cat No : CM03348

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Synonyms

LY-3475070|EX-A4254

验证数据展示

  • CAS No.: 2375815-63-5

    CD73-IN-3
    CAS#: 2375815-63-5

产品信息

LY-3475070 is a potent and selective CD73 inhibitor with an IC50 of 28 nM, and its use alone or in combination with pembrolizumab is currently being tested in patients with advanced cancer.

CAS号 2375815-63-5
分子式 C15H18N4O2
主要靶点 CD73
主要通路 免疫与炎症
分子量 286.33
纯度 99.59%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 LY-3475070|EX-A4254

靶点活性

CD73:28 nM

溶解度

DMSO:22.5 mg/mL (78.58 mM)

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2