验证数据展示
产品信息
60211-1-PBS targets LYN in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.
Tested Applications | WB, IHC, IF/ICC, Indirect ELISA Application Description |
Tested Reactivity | human, mouse |
Immunogen | LYN fusion protein Ag12723 种属同源性预测 |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Full Name | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog |
Synonyms | JTK8, LYN, Tyrosine protein kinase Lyn |
Calculated Molecular Weight | 512 aa, 59 kDa |
Observed Molecular Weight | 56 kDa |
GenBank Accession Number | BC075002 |
Gene Symbol | LYN |
Gene ID (NCBI) | 4067 |
RRID | AB_10949077 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P07948 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
LYN, also named as JTK8, p53Lyn and p56Lyn, belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. It is a non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors and plays an important role in the regulation of innate and adaptive immune responses, hematopoiesis, responses to growth factors and cytokines, integrin signaling, but also responses to DNA damage and genotoxic agents. LYN is a component of the mTOR (mammalian target of rapamycin) pathway.