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LYN Monoclonal antibody, PBS Only

LYN Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

human, mouse

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3C7F2

Cat no : 60211-1-PBS

Print datasheet

Synonyms

JTK8, LYN, Tyrosine protein kinase Lyn

验证数据展示

  • WB analysis of Jurkat using 60211-1-Ig (same clone as 60211-1-PBS)

    WB analysis of Jurkat using 60211-1-Ig (same clone as 60211-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 60211-1-Ig (LYN antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60211-1-PBS in a different storage buffer formulation.

  • IHC staining of human placenta using 60211-1-Ig (same clone as 60211-1-PBS)

    IHC staining of human placenta using 60211-1-Ig (same clone as 60211-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 60211-1-Ig (LYN Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 60211-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with LYN antibody included
  • IHC staining of human placenta using 60211-1-Ig (same clone as 60211-1-PBS)

    IHC staining of human placenta using 60211-1-Ig (same clone as 60211-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 60211-1-Ig (LYN Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 60211-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with LYN antibody included
  • IF Staining of HepG2 using 60211-1-Ig (same clone as 60211-1-PBS)

    IF Staining of HepG2 using 60211-1-Ig (same clone as 60211-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using LYN antibody (60211-1-Ig, Clone: 3C7F2 ) at dilution of 1:800 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 60211-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy LYN Ready-To-Use IHC Kit. LYN primary antibody included.

产品信息

60211-1-PBS targets LYN in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, IHC, IF/ICC, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen LYN fusion protein Ag12723 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
Synonyms JTK8, LYN, Tyrosine protein kinase Lyn
Calculated Molecular Weight 512 aa, 59 kDa
Observed Molecular Weight 56 kDa
GenBank Accession NumberBC075002
Gene Symbol LYN
Gene ID (NCBI) 4067
RRIDAB_10949077
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP07948
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

LYN, also named as JTK8, p53Lyn and p56Lyn, belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. It is a non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors and plays an important role in the regulation of innate and adaptive immune responses, hematopoiesis, responses to growth factors and cytokines, integrin signaling, but also responses to DNA damage and genotoxic agents. LYN is a component of the mTOR (mammalian target of rapamycin) pathway.