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Livin Polyclonal antibody, PBS Only

Livin Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 27543-1-PBS

Print datasheet

Synonyms

验证数据展示

  • WB analysis using 27543-1-AP (same clone as 27543-1-PBS)

    WB analysis using 27543-1-AP (same clone as 27543-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27543-1-AP (Livin antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27543-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 27543-1-AP (same clone as 27543-1-PBS)

    IHC staining of human breast cancer using 27543-1-AP (same clone as 27543-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 27543-1-AP (Livin antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27543-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 27543-1-AP (same clone as 27543-1-PBS)

    IHC staining of human breast cancer using 27543-1-AP (same clone as 27543-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 27543-1-AP (Livin antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27543-1-PBS in a different storage buffer formulation.

产品信息

27543-1-PBS targets Livin in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen Livin fusion protein Ag26737 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name baculoviral IAP repeat-containing 7
Synonyms
Calculated Molecular Weight 33 kDa
Observed Molecular Weight 33 kDa
GenBank Accession NumberBC014475
Gene Symbol Livin
Gene ID (NCBI) 79444
RRIDAB_2880901
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ96CA5
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

BIRC7 also known as Livin, is one of the family members of the inhibitor of apoptosis protein (IAP). BIRC7 contains a BIR domain that has been shown to bind and inhibit caspases-3, −7 and −9, playing a key role in inhibiting apoptosis. Overexpression of BIRC7 in tumors has been linked with increased chemo- and radio-resistance, recurrence, and decreased patient survival. BIRC7 is closely associated with melanoma disease progression, apoptosis resistance, and chemotherapeutic drug resistance.