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Host
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Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
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Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 85343-1-RR (same clone as 85343-1-PBS)

    WB analysis using 85343-1-RR (same clone as 85343-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85343-1-RR (LUM antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85343-1-PBS in a different storage buffer formulation.

  • WB analysis of Recombinant protein using 85343-1-RR (same clone as 85343-1-PBS)

    WB analysis of Recombinant protein using 85343-1-RR (same clone as 85343-1-PBS)

    Recombinant protein were subjected to SDS PAGE followed by western blot with 85343-1-RR (LUM antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85343-1-PBS in a different storage buffer formulation.

Lumican Recombinant antibody, PBS Only

Lumican Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 85343-1-PBS

产品说明书

CloneNo. 242615H3

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

LUM, SLRR2D, LDC, KSPG lumican, 242615H3

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

85343-1-PBS targets Lumican in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 lumican
别名 LUM, SLRR2D, LDC, KSPG lumican, 242615H3
计算分子量38 kDa
观测分子量50-90 kDa
GenBank蛋白编号NM_002345.3
基因名称 Lumican
Gene ID (NCBI) 4060
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP51884
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Lumican (LUM), a member of the small leucine-rich proteoglycan (SLRP) family, is one of the major extracellular components in interstitial collagenous matrices of the corneal stroma, aorta, skin, skeletal muscle, lung, kidney, bone, cartilage, and intervertebral discs. SLRPs constitute an important fraction of noncollagenous extracellular matrix proteins and have important effects on cell behavior. Lumican regulates collagenous matrix assembly as a keratan sulfate proteoglycan in the cornea and may exist as a glycoprotein in the connective tissues of other organs. Posttranslational modifications lumican goes through can increase its apparent molecular weight to 50-90 kDa. Studies show that lumican participates in the maintenance of tissue homeostasis and modulates cellular functions including cell proliferation, migration, and differentiation. (PMID: 18949819; 22252641; 9761754; 22365843)