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M1001

M1001 是较弱的HIF-2α激动剂，直接与 HIF-2α PAS-B 结构域结合，Kd=667 nM，能够提高 HIF-2α-ARNT 复合体之间的稳定性。

CAS号

874590-32-6

分子式

C17H17N3O2S

主要靶点

HIF|HIF/HIF Prolyl-Hydroxylase

仅限科研使用

Cat No : CM04461

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Synonyms

验证数据展示

  • CAS No.: 874590-32-6

    M1001
    CAS#: 874590-32-6

产品信息

M1001 is a HIF-2α agonist.

CAS号 874590-32-6
分子式 C17H17N3O2S
主要靶点 HIF|HIF/HIF Prolyl-Hydroxylase
主要通路 表观遗传|代谢|血管生成
分子量 327.4
纯度 100.00%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名

靶点活性

HIF-2α:667 nM(Kd)

溶解度

DMSO:250 mg/mL (763.59 mM)

参考文献

1.Bidirectional Modulation of HIF-2 Activity through Chemical Ligands[C]// 0.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2