验证数据展示
产品信息
19702-1-AP targets MAP3K4-Specific in ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 | Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | mitogen-activated protein kinase kinase kinase 4 |
| 别名 | KIAA0213, MAP three kinase 1, MAP3K4, MAPK/ERK kinase kinase 4, MAPKKK4, MEK kinase 4, MEKK 4, MEKK4, MTK1, PRO0412 |
| 计算分子量 | 182 kDa |
| GenBank蛋白编号 | NM_005922 |
| 基因名称 | MAP3K4 |
| Gene ID (NCBI) | 4216 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9Y6R4 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
MAP3K4, also named as KIAA0213, MAPKKK4, MEKK4 and MTK1, belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and MAP kinase kinase kinase subfamily. MAP3K4 is a component of a protein kinase signal transduction cascade. MAP3K4 activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. MAP3K4 specifically phosphorylates and activates MAP2K4 and MAP2K6. This antibody is specific to isoform1 and 2 of MAP3K4.