• Featured Product
  • KD/KO Validated

MAX Polyclonal antibody

MAX Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (1)

Applications

WB, ELISA and More (3)

Conjugate

Unconjugated

Cat No : 10426-1-AP

Print datasheet

Synonyms

bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8, MAX, MYC associated factor X, orf1, Protein max



经过测试的应用

Positive WB detected inHEK-293 cells, PC-3 cells
Planning an IHC experiment? We recommend our IHCeasy MAX Ready-To-Use IHC Kit. MAX primary antibody included.

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

10426-1-AP targets MAX in WB, IHC, IF, ChIP, ELISA applications and shows reactivity with human samples.

Tested Applications WB, ELISA
Cited Applications chIP, IF, IHC, WB
Tested Reactivity human
Cited Reactivityhuman, mouse
Immunogen MAX fusion protein Ag0680 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name MYC associated factor X
Synonyms bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8, MAX, MYC associated factor X, orf1, Protein max
Calculated Molecular Weight 18 kDa
Observed Molecular Weight 22 kDa
GenBank Accession NumberBC003525
Gene Symbol MAX
Gene ID (NCBI) 4149
RRIDAB_2141660
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP61244
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Max, a member of MAX family, contains a basic helix-loop-helix (bHLH) domain, is a transcription regulator. MAX can form a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC-MAX complex is a transcriptional activator, while the MAD-MAX complex is a repressor. MAX could dimerizated with another bHLH protein to form a heterodimer, such MYC or MAD. Thus bands recognized by this antibody much larger than predicted.

实验方案

Product Specific Protocols
WB protocol for MAX antibody 10426-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouseWB

Cancer Cell

MAX Functions as a Tumor Suppressor and Rewires Metabolism in Small Cell Lung Cancer.

Authors - Arnaud Augert
  • KO Validated
humanWB

Sci Adv

A MYC inhibitor selectively alters the MYC and MAX cistromes and modulates the epigenomic landscape to regulate target gene expression.

Authors - Austin G Holmes
humanWB

Nat Commun

PCGF6 controls neuroectoderm specification of human pluripotent stem cells by activating SOX2 expression.

Authors - Xianchun Lan
humanWB,ChIP

Elife

Loss of MGA repression mediated by an atypical polycomb complex promotes tumor progression and invasiveness.

Authors - Haritha Mathsyaraja
humanWB

Cell Commun Signal

Novel dual-targeting c-Myc inhibitor D347-2761 represses myeloma growth via blocking c-Myc/Max heterodimerization and disturbing its stability.

Authors - Ruosi Yao
humanchIP

J Biol Chem

Role for carbohydrate response element-binding protein (ChREBP) in high glucose-mediated repression of long noncoding RNA Tug1.

Authors - Jianyin Long