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MC-Val-Ala-PAB-PNP

MC-Val-Ala-PAB-PNP 是一种用于合成抗体偶联药物的 linker，可降解。

CAS号

1639939-40-4

分子式

C32H37N5O10

主要靶点

Others

仅限科研使用

Cat No : CM02508

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Synonyms

验证数据展示

  • CAS No.: 1639939-40-4

    MC-Val-Ala-PAB-PNP
    CAS#: 1639939-40-4

产品信息

MC-Val-Ala-PAB-PNP is a cleavable ADC linker. MC-Val-Ala-PAB-PNP can be used in the synthesis of antibody-drug conjugates (ADCs).

CAS号 1639939-40-4
分子式 C32H37N5O10
主要靶点 Others
主要通路 其他
分子量 651.66
纯度 96.71%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名

体外活性

ADCs consist of an antibody attached to an ADC cytotoxin through an ADC linker.

溶解度

DMSO:50 mg/mL (76.73 mM),Sonification is recommended.

参考文献

1.Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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=
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C1   V1   C2   V2