M-CSF Polyclonal antibody

M-CSF Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (1)

Applications

ELISA and More (3)

Conjugate

Unconjugated

Cat no : 14779-1-AP

Print datasheet

Synonyms

CSF 1, CSF1, Lanimostim, M CSF, MCSF, M-CSF



产品信息

14779-1-AP targets M-CSF in WB, IF, ELISA, Cell treatment applications and shows reactivity with human samples.

Tested Applications ELISA Application Description
Cited ApplicationsWB, IF, Cell treatment
Tested Reactivity human
Cited Reactivityhuman, mouse
Immunogen M-CSF fusion protein Ag6294 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name colony stimulating factor 1 (macrophage)
Synonyms CSF 1, CSF1, Lanimostim, M CSF, MCSF, M-CSF
Calculated Molecular Weight 60 kDa
Observed Molecular Weight 70 kDa
GenBank Accession NumberBC021117
Gene Symbol M-CSF
Gene ID (NCBI) 1435
RRIDAB_10643241
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP09603
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Colony stimulating factor-1 (CSF-1) is a homodimeric glycoprotein that humorally regulates the proliferation and differentiation of mononuclear phagocytic cells and locally regulates cells of the female reproductive tract. Alternative splicing of the human CSF-1 mRNA leads to alternative expression of the CSF-1 homodimer as a secreted glycoprotein or as a membrane-spanning molecule with cell surface biological activity. CSF-1 is predominantly secreted as highly sulfated species of 375- and 250-kDa with a smaller amount of a 100-kDa species. The three predominant CSF-1 species were shown to be an 80-kDa homodimer, an 80-kDa/50-kDa heterodimer, and a 50-kDa homodimer. (PMID: 1733926) This antibody could recognieze 60 kDa, 48 kDa, 29 kDa isoforms.

发表文章

SpeciesApplicationTitle
mouseWB

J Control Release

Chemoattractants driven and microglia based biomimetic nanoparticle treating TMZ-resistant glioblastoma multiforme.

Authors - Sai Qiao
mouseWB,Cell treatment

J Nanobiotechnology

Biomimetic GBM-targeted drug delivery system boosting ferroptosis for immunotherapy of orthotopic drug-resistant GBM.

Authors - Bao Liu
WB

Biomed Pharmacother

Anti-osteoporotic effects of alisol C 23-acetate via osteoclastogenesis inhibition.

Authors - Xiaokang Jia
humanWB

Int J Biol Sci

Macrophage Colony-stimulating Factor Mediates the Recruitment of Macrophages in Triple negative Breast Cancer.

Authors - Xiaoqing Lu
human,mouseWB

Invest Ophthalmol Vis Sci

CSF1/CSF1R-mediated Crosstalk Between Choroidal Vascular Endothelial Cells and Macrophages Promotes Choroidal Neovascularization.

Authors - Yamei Zhou
mouseWB

Front Physiol

Heat Stress Modulates a Placental Immune Response Associated With Alterations in the Development of the Fetal Intestine and Its Innate Immune System in Late Pregnant Mouse.

Authors - Huiduo Guo