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MDL-28170

MDL-28170 (Calpain Inhibitor III) 是一种选择性的、有效的、具有膜渗透性的半胱氨酸蛋白酶 (calpain)抑制剂，可在全身给药后迅速穿过血脑屏障。它还能阻断γ-secretase。

CAS号

88191-84-8

分子式

C22H26N2O4

主要靶点

Cysteine Protease|Proteasome

仅限科研使用

Cat No : CM03312

Print datasheet

Synonyms

Calpain Inhibitor III

验证数据展示

  • CAS No.: 88191-84-8

    MDL-28170
    CAS#: 88191-84-8

产品信息

MDL-28170 (Calpain Inhibitor III) is a Cysteine protease.

CAS号 88191-84-8
分子式 C22H26N2O4
主要靶点 Cysteine Protease|Proteasome
主要通路 泛素化|蛋白酶体
分子量 382.45
纯度 ， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 Calpain Inhibitor III

溶解度

DMSO:10 mM,DMSO:25 mg/mL (65.36 mM),Sonification/heating is recommended.

参考文献

1.Li PA, et al. Postischemic treatment with calpain inhibitor MDL 28170 ameliorates brain damage in a gerbil model of global ischemia. Neurosci Lett. 1998 May 8;247(1):17-20. 2.Ai J, et al. Calpain inhibitor MDL-28170 reduces the functional and structural deterioration of corpus callosum following fluid percussion injury. J Neurotrauma. 2007 Jun;24(6):960-78.

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