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  • Featured Product
  • KD/KO Validated

Mouse MECR Polyclonal antibody, PBS Only

MECR Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 51025-2-PBS

Print datasheet

Synonyms

验证数据展示

  • WB analysis of mouse skeletal muscle using 51025-2-Ig (same clone as 51025-2-PBS)

    WB analysis of mouse skeletal muscle using 51025-2-Ig (same clone as 51025-2-PBS)

    mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 51025-2-Ig (MECR antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 51025-2-PBS in a different storage buffer formulation.

  • IHC staining of mouse skeletal muscle using 51025-2-Ig (same clone as 51025-2-PBS)

    IHC staining of mouse skeletal muscle using 51025-2-Ig (same clone as 51025-2-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue slide using 51025-2-Ig (MECR antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 51025-2-PBS in a different storage buffer formulation.

产品信息

51025-2-PBS targets MECR in WB, IHC, Indirect ELISA applications and shows reactivity with mouse samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity mouse
Immunogen Peptide 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name mitochondrial trans-2-enoyl-CoA reductase
Synonyms
Calculated Molecular Weight 40 kDa
Observed Molecular Weight 65 kDa
GenBank Accession NumberBC003864
Gene Symbol MECR
Gene ID (NCBI) 26922
RRIDAB_1167469
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9DCS3
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Mitochondrial Trans-2-Enoyl-CoA Reductase is abbrivated as MECR, involved in human mitochonrial fatty acid synthesis(mtFAS) as an oxidoreductase. (PMID: 27817865) MECR has molecular weight can be calculated around 37KDa. With immunopercipitation reaction on mouse heart samples, the IgG heavy chain, dimer of MECR is around 65KDa. Numerous studies have shown disorder of lipid metabolism is closely related with malignance, especially in liver cancer. As futher research suggests that MECR has close realitionship with cell prolifereation, appotosis, and metastasis (PMID: 31178528)