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验证数据展示

  • WB analysis of mouse skeletal muscle using 51025-2-Ig (same clone as 51025-2-PBS)

    WB analysis of mouse skeletal muscle using 51025-2-Ig (same clone as 51025-2-PBS)

    mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 51025-2-Ig (MECR antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 51025-2-PBS in a different storage buffer formulation.

  • IHC staining of mouse skeletal muscle using 51025-2-Ig (same clone as 51025-2-PBS)

    IHC staining of mouse skeletal muscle using 51025-2-Ig (same clone as 51025-2-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue slide using 51025-2-Ig (MECR antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 51025-2-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

Mouse MECR Polyclonal antibody, PBS Only

MECR Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 51025-2-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

51025-2-PBS targets MECR in WB, IHC, Indirect ELISA applications and shows reactivity with mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 mouse
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 mitochondrial trans-2-enoyl-CoA reductase
别名
计算分子量 40 kDa
观测分子量 65 kDa
GenBank蛋白编号BC003864
基因名称 MECR
Gene ID (NCBI) 26922
RRIDAB_1167469
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ9DCS3
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Mitochondrial Trans-2-Enoyl-CoA Reductase is abbrivated as MECR, involved in human mitochonrial fatty acid synthesis(mtFAS) as an oxidoreductase. (PMID: 27817865) MECR has molecular weight can be calculated around 37KDa. With immunopercipitation reaction on mouse heart samples, the IgG heavy chain, dimer of MECR is around 65KDa. Numerous studies have shown disorder of lipid metabolism is closely related with malignance, especially in liver cancer. As futher research suggests that MECR has close realitionship with cell prolifereation, appotosis, and metastasis (PMID: 31178528)