• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0
Use Able AI chat for product recommendations

验证数据展示

  • WB analysis of SH-SY5Y using 10056-1-AP (same clone as 10056-1-PBS)

    WB analysis of SH-SY5Y using 10056-1-AP (same clone as 10056-1-PBS)

    SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 10056-1-AP (MEF2C antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10056-1-PBS in a different storage buffer formulation.

  • IP experiment of SH-SY5Y using 10056-1-AP (same clone as 10056-1-PBS)

    IP experiment of SH-SY5Y using 10056-1-AP (same clone as 10056-1-PBS)

    IP result of anti-MEF2C (IP:10056-1-AP, 3ug; Detection:10056-1-AP 1:500) with SH-SY5Y cells lysate 2000ug. This data was developed using the same antibody clone with 10056-1-PBS in a different storage buffer formulation.

  • IHC staining of human lymphoma using 10056-1-AP (same clone as 10056-1-PBS)

    IHC staining of human lymphoma using 10056-1-AP (same clone as 10056-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lymphoma using 10056-1-AP (MEF2C antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 10056-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with MEF2C antibody included
  • WB analysis using 10056-1-AP (same clone as 10056-1-PBS)

    WB analysis using 10056-1-AP (same clone as 10056-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 10056-1-AP (MEF2C antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10056-1-PBS in a different storage buffer formulation.

  • IF Staining of HepG2 using 10056-1-AP (same clone as 10056-1-PBS)

    IF Staining of HepG2 using 10056-1-AP (same clone as 10056-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using MEF2C antibody (10056-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-Phalloidin (red). This data was developed using the same antibody clone with 10056-1-PBS in a different storage buffer formulation.

  • FC experiment of HeLa using 10056-1-AP (same clone as 10056-1-PBS)

    FC experiment of HeLa using 10056-1-AP (same clone as 10056-1-PBS)

    1X10^6 HeLa cells were intracellularly stained with 0.4 ug Anti-Human MEF2C (10056-1-AP) and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) at dilution 1:1000 (red), or 0.4 ug Isotype Control. Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer. This data was developed using the same antibody clone with 10056-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

MEF2C Polyclonal antibody, PBS Only

MEF2C Polyclonal Antibody for WB, IHC, IF/ICC, FC (Intra), IP, Indirect ELISA
Cat No. 10056-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, IF/ICC, FC (Intra), IP, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

Planning an IHC experiment? We recommend our IHCeasy MEF2C Ready-To-Use IHC Kit. MEF2C primary antibody included.

产品信息

10056-1-PBS targets MEF2C in WB, IHC, IF/ICC, FC (Intra), IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, IF/ICC, FC (Intra), IP, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag0020

Product name: Recombinant human MEF2C protein

Source: e coli.-derived, Unknow

Tag: N/A

Domain: MEF2C of BC156603

Sequence:

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 myocyte enhancer factor 2C
别名
计算分子量 51 kDa
观测分子量45-70 kDa
GenBank蛋白编号BC156603
基因名称 MEF2C
Gene ID (NCBI) 4208
RRIDAB_513447
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ06413
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

MEF2C belongs to the MEF2 family. It is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. MEF2C controls cardiac morphogenesis and myogenesis, and is also involved in vascular development[PMID: 20221419]. It plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission[PMID:18599438]. It is crucial for normal neuronal development, distribution, and electrical activity in the neocortex and is necessary for proper development of megakaryocytes and platelets and for bone marrow B lymphopoiesis[PMID: 21666133]. This protein is required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B cells. It may also be involved in neurogenesis and in the development of cortical architecture. MEF2C exists some isoforms with MV 50-52 kDa, 47 kDa, and 45 kDa, but modified MEF2C is about 55-66 kDa.

||
New chat Able
正在加载，请稍候...