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Host
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Species Reactivity
0
Species Reactivity
0
Conjugate
0
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Compatible Species
0
Conjugate
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验证数据展示

  • WB analysis using 66384-1-Ig (same clone as 66384-1-PBS)

    WB analysis using 66384-1-Ig (same clone as 66384-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66384-1-Ig (MICA antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66384-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 66384-1-Ig (same clone as 66384-1-PBS)

    IHC staining of human tonsillitis using 66384-1-Ig (same clone as 66384-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 66384-1-Ig (MICA Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66384-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 66384-1-Ig (same clone as 66384-1-PBS)

    IHC staining of human tonsillitis using 66384-1-Ig (same clone as 66384-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 66384-1-Ig (MICA Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66384-1-PBS in a different storage buffer formulation.

MICA Monoclonal antibody, PBS Only

MICA Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 66384-1-PBS

产品说明书

CloneNo. 1E2C8

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

MIC A, MICA, PERB11.1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

66384-1-PBS targets MICA in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原 MICA fusion protein Ag3298 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 MHC class I polypeptide-related sequence A
别名 MIC A, MICA, PERB11.1
计算分子量 383 aa, 43 kDa
观测分子量 43-50 kDa
GenBank蛋白编号BC016929
基因名称 MICA
Gene ID (NCBI) 100507436
RRIDAB_2881760
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ29983
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Human MHC class I chain-related genes located within the HLA class I region of chromosome 6 encode MHC class I chain-related A and B (MICA and MICB) (PMID: 11429322). MICA and MICB are stress-inducible surface molecules that are not associated with β2-microglobulin and do not present peptides (PMID: 9497295). They are expressed in intestinal epithelium and many epithelial tumors (PMID: 10359807). MICA and MICB are ligands for NKG2D which is an activating receptor that is expressed on most natural killer (NK) cells, CD8 αβ T cells, and γδ T cells (PMID: 10426993, 11491531).