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MICA Recombinant antibody, PBS Only

MICA Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

242004C2

Cat no : 84850-5-PBS

Print datasheet

Synonyms

MIC-A, MIC A, 242004C2

验证数据展示

  • WB analysis of HeLa using 84850-5-RR (same clone as 84850-5-PBS)

    WB analysis of HeLa using 84850-5-RR (same clone as 84850-5-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 84850-5-RR (MICA antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84850-5-PBS in a different storage buffer formulation.

产品信息

84850-5-PBS targets MICA in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human
Immunogen Recombinant protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name MHC class I polypeptide-related sequence A
Synonyms MIC-A, MIC A, 242004C2
Calculated Molecular Weight 383 aa, 43 kDa
Observed Molecular Weight58 kDa
GenBank Accession NumberBC016929
Gene Symbol MICA
Gene ID (NCBI) 100507436
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ29983
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Human MHC class I chain-related genes located within the HLA class I region of chromosome 6 encode MHC class I chain-related A and B (MICA and MICB) (PMID: 11429322). MICA and MICB are stress-inducible surface molecules that are not associated with β2-microglobulin and do not present peptides (PMID: 9497295). They are expressed in intestinal epithelium and many epithelial tumors (PMID: 10359807). MICA and MICB are ligands for NKG2D which is an activating receptor that is expressed on most natural killer (NK) cells, CD8 αβ T cells, and γδ T cells (PMID: 10426993, 11491531).