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MIER2 Polyclonal antibody

MIER2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 17426-1-AP

Print datasheet

Synonyms

Mi-er2, Mesoderm induction early response protein 2, KIAA1193

验证数据展示

  • WB analysis using 17426-1-AP

    WB analysis using 17426-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 17426-1-AP (MIER2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inHepG2 cells, HeLa cells, Jurkat cells, MCF-7 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

17426-1-AP targets MIER2 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen MIER2 fusion protein Ag11491 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name mesoderm induction early response 1, family member 2
Synonyms Mi-er2, Mesoderm induction early response protein 2, KIAA1193
Calculated Molecular Weight 545 aa, 60 kDa
Observed Molecular Weight65-70 kDa
GenBank Accession NumberBC028203
Gene Symbol MIER2
Gene ID (NCBI) 54531
RRIDAB_2143931
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ8N344
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Mesoderm induction early response 2 (MIER2) is a member of the MIER family of proteins, which is relatively conservative in evolution and includes three members: MIER1, MIER2, and MIER3. The MIER family is known to contribute to histone deacetylase (HDAC) activity and actively participate in histone deacetylation (PMID: 28046085; PMID: 38702028). In renal cell carcinoma, MIER2 represses PGC1A expression by recruiting HDAC1 to deacetylate P53 (PMID: 28046085).

实验方案

Product Specific Protocols
WB protocol for MIER2 antibody 17426-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols