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Conjugate
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MIER2 Polyclonal antibody, PBS Only

MIER2 Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 17426-1-PBS

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Synonyms

验证数据展示

  • WB analysis using 17426-1-AP (same clone as 17426-1-PBS)

    WB analysis using 17426-1-AP (same clone as 17426-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 17426-1-AP (MIER2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17426-1-PBS in a different storage buffer formulation.

产品信息

17426-1-PBS targets MIER2 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen MIER2 fusion protein Ag11491 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name mesoderm induction early response 1, family member 2
Synonyms
Calculated Molecular Weight 545 aa, 60 kDa
Observed Molecular Weight65-70 kDa
GenBank Accession NumberBC028203
Gene Symbol MIER2
Gene ID (NCBI) 54531
RRIDAB_2143931
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ8N344
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Mesoderm induction early response 2 (MIER2) is a member of the MIER family of proteins, which is relatively conservative in evolution and includes three members: MIER1, MIER2, and MIER3. The MIER family is known to contribute to histone deacetylase (HDAC) activity and actively participate in histone deacetylation (PMID: 28046085; PMID: 38702028). In renal cell carcinoma, MIER2 represses PGC1A expression by recruiting HDAC1 to deacetylate P53 (PMID: 28046085).