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Conjugate
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MIER3 Polyclonal antibody, PBS Only

MIER3 Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 17543-1-PBS

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Synonyms

验证数据展示

  • WB analysis of mouse uterus using 17543-1-AP (same clone as 17543-1-PBS)

    WB analysis of mouse uterus using 17543-1-AP (same clone as 17543-1-PBS)

    mouse uterus tissue were subjected to SDS PAGE followed by western blot with 17543-1-AP (MIER3 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17543-1-PBS in a different storage buffer formulation.

产品信息

17543-1-PBS targets MIER3 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen MIER3 fusion protein Ag11604 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name mesoderm induction early response 1, family member 3
Synonyms
Calculated Molecular Weight 522 aa, 59 kDa
Observed Molecular Weight 55 kDa
GenBank Accession NumberBC041348
Gene Symbol MIER3
Gene ID (NCBI) 166968
RRIDAB_2143938
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ7Z3K6
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The mesoderm induction early response (MIER) protein family is known as fibroblast growth factor (FGF)-regulated immediate-early protein family. Activated by FGF, MIER proteins may have a pivotal role in FGF-regulated cellular activities, indicating a potential influence in the progression of certain cancers [PMID:15117948]. MIER3 localizes to the nucleus and primarily functions as a transcriptional repressor. Rat mammary carcinoma susceptibility 1b (Mcs1b) is a quantitative trait locus on RN02 that confers decreased susceptibility when Copenhagen (COP)-resistant alleles are introgressed into a Wistar Furth (WF)-susceptible genome. MIER3 is a candidate Mcs1b gene [PMID:22993404].