MIG6; ERRFI1 Recombinant antibody
MIG6; ERRFI1 Recombinant Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human
Applications
WB, ELISA
Conjugate
Unconjugated
CloneNo.
240447C3
验证数据展示
经过测试的应用
Positive WB detected in | HCT 116 cells, HepG2 |
推荐稀释比
Application | Dilution |
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Western Blot (WB) | WB : 1:5000-1:50000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
The immunogen of 83475-2-RR is MIG6; ERRFI1 Fusion Protein expressed in E. coli.
Tested Applications | WB, ELISA Application Description |
Tested Reactivity | Human |
Immunogen | MIG6; ERRFI1 fusion protein Ag33341 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | ERBB receptor feedback inhibitor 1 |
Synonyms | ERRFI1, 240447C3, MIG-6, MIG6, MIG 6 |
Calculated Molecular Weight | 51kd |
Observed Molecular Weight | 51 kDa |
GenBank Accession Number | NM_018948 |
Gene Symbol | MIG6 |
Gene ID (NCBI) | 54206 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q9UJM3 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
ERRFI1 (the product of mitogen-inducible gene 6, also known as MIG6) is an early response gene encoding a non-kinase scaffold adaptor protein induced by various stimuli such as hormones and stresses. ERRFI1 is considered a negative regulator of EGFR because it can directly bind to EGFR, inhibit the catalytic activity of EGFR, and mediate EGFR lysosomal degradation. ERRFI1 may play important roles in regulating stress response, maintaining homeostasis in tissues like joints or cardiac muscle, and functioning as a tumor suppressor.
实验方案
Product Specific Protocols | |
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WB protocol for MIG6; ERRFI1 antibody 83475-2-RR | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |