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验证数据展示

  • IF Staining of HeLa using 66049-1-Ig (same clone as 66049-1-PBS)

    IF Staining of HeLa using 66049-1-Ig (same clone as 66049-1-PBS)

    Immunofluorescent analysis of fixed Hela cells using 66049-1-Ig (MMS19 antibody) at dilution of 1:50 and Rhodamine-Goat anti-Mouse IgG. This data was developed using the same antibody clone with 66049-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse testis using 66049-1-Ig (same clone as 66049-1-PBS)

    IHC staining of mouse testis using 66049-1-Ig (same clone as 66049-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 66049-1-Ig (MMS19 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66049-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with MMS19 antibody included
  • IHC staining of mouse testis using 66049-1-Ig (same clone as 66049-1-PBS)

    IHC staining of mouse testis using 66049-1-Ig (same clone as 66049-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 66049-1-Ig (MMS19 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66049-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with MMS19 antibody included
  • WB analysis of HeLa using 66049-1-Ig (same clone as 66049-1-PBS)

    WB analysis of HeLa using 66049-1-Ig (same clone as 66049-1-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 66049-1-Ig (MMS19 Antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66049-1-PBS in a different storage buffer formulation.

  • IP experiment of mouse brain using 66049-1-Ig (same clone as 66049-1-PBS)

    IP experiment of mouse brain using 66049-1-Ig (same clone as 66049-1-PBS)

    IP result of anti-MMS19 (IP:66049-1-Ig, 4ug; Detection:66049-1-Ig 1:2000) with mouse brain tissue lysate 4000ug. This data was developed using the same antibody clone with 66049-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

MMS19 Monoclonal antibody, PBS Only

MMS19 Monoclonal Antibody for WB, IHC, IF/ICC, IP, Indirect ELISA
Cat No. 66049-1-PBS

产品说明书

CloneNo. 2H6D8

宿主/亚型

Mouse / IgG2b

种属反应性

human, mouse, rat

应用

WB, IHC, IF/ICC, IP, Indirect ELISA

别名

hMMS19, MET18, MET18 homolog, MMS19, MMS19 like protein, MMS19L

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy MMS19 Ready-To-Use IHC Kit. MMS19 primary antibody included.

产品信息

66049-1-PBS targets MMS19 in WB, IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF/ICC, IP, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 MMS19 fusion protein Ag8960 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 MMS19 nucleotide excision repair homolog (S. cerevisiae)
别名 hMMS19, MET18, MET18 homolog, MMS19, MMS19 like protein, MMS19L
计算分子量 1030 aa, 113 kDa
观测分子量 103 kDa, 38 kDa
GenBank蛋白编号BC006575
基因名称 MMS19
Gene ID (NCBI) 64210
RRIDAB_11041708
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ96T76
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

MMS19 (MMS19 nucleotide excision repair homolog), also known as MET18, is a 1,030 amino acid nuclear protein containing seven HEAT repeats that belongs to the MET18/MMS19 family. Via its interactions with TFIIH p80 and TFIIH p89 helicases, MMS19 plays a role in nucleotide excision repair (NER) and RNA polymerase II (Pol II) transcription. MMS19 may also function as a transcriptional coactivator of estrogen receptor. While ubiquitously expressed, highest levels of MMS19 have been found in testis. At least five distinct MMS19 protein isoforms exist, which are produced by alternative splicing events.