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MN-64

MN-64 是一种有效的tankyrase 1抑制剂，对TNKS1、TNKS2、ARTD1 和 ARTD2 的IC50值分别为 6、72、19.1 和 39.4 μM。

CAS号

92831-11-3

分子式

C18H16O2

主要靶点

PARP|Others|Wnt/beta-catenin

仅限科研使用

Cat No : CM05754

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Synonyms

MN64

验证数据展示

  • CAS No.: 92831-11-3

    MN-64
    CAS#: 92831-11-3

产品信息

MN-64 is a tankyrases inhibitor, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.

CAS号 92831-11-3
分子式 C18H16O2
主要靶点 PARP|Others|Wnt/beta-catenin
主要通路 DNA损伤和修复|干细胞|细胞骨架|表观遗传|其他
分子量 264.32
纯度 99.36%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 MN64

靶点活性

ARTD2:39.4 μM|TNKS2:72 nM|ARTD1:19.1 μM|TNKS1:6 nM

溶解度

DMSO:12 mg/mL (45.4 mM)

参考文献

1.Narwal M, et al. J Med Chem. 2013 Oct 24;56(20):7880-9.

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