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  • Featured Product
  • KD/KO Validated

MOV10 Polyclonal antibody, PBS Only

MOV10 Polyclonal Antibody for WB, IHC, IF/ICC, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF/ICC, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 10370-1-PBS

Print datasheet

Synonyms

验证数据展示

  • WB analysis using 10370-1-AP (same clone as 10370-1-PBS)

    WB analysis using 10370-1-AP (same clone as 10370-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 10370-1-AP (MOV10 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10370-1-PBS in a different storage buffer formulation.

  • IP experiment of Hepg2 using 10370-1-AP (same clone as 10370-1-PBS)

    IP experiment of Hepg2 using 10370-1-AP (same clone as 10370-1-PBS)

    IP result of anti-MOV10 (IP:10370-1-AP, 4ug; Detection:10370-1-AP 1:300) with Hepg2 cells lysate 3000 ug. This data was developed using the same antibody clone with 10370-1-PBS in a different storage buffer formulation.

  • IHC staining of human prostate hyperplasia using 10370-1-AP (same clone as 10370-1-PBS)

    IHC staining of human prostate hyperplasia using 10370-1-AP (same clone as 10370-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human prostate hyperplasia tissue slide using 10370-1-AP (MOV10 antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 10370-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with MOV10 antibody included
  • IHC staining of human prostate hyperplasia using 10370-1-AP (same clone as 10370-1-PBS)

    IHC staining of human prostate hyperplasia using 10370-1-AP (same clone as 10370-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human prostate hyperplasia tissue slide using 10370-1-AP (MOV10 antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 10370-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with MOV10 antibody included
  • IF Staining of HepG2 using 10370-1-AP (same clone as 10370-1-PBS)

    IF Staining of HepG2 using 10370-1-AP (same clone as 10370-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using MOV10 antibody (10370-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 10370-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy MOV10 Ready-To-Use IHC Kit. MOV10 primary antibody included.

产品信息

10370-1-PBS targets MOV10 in WB, IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, IF/ICC, IP, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen MOV10 fusion protein Ag0384 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name Mov10, Moloney leukemia virus 10, homolog (mouse)
Synonyms
Calculated Molecular Weight 114 kDa
Observed Molecular Weight 110-115 kDa
GenBank Accession NumberBC002548
Gene Symbol MOV10
Gene ID (NCBI) 4343
RRIDAB_2297897
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9HCE1
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

MOV10, also named as KIAA1631, belongs to the DNA2/NAM7 helicase family and SDE3 subfamily. It is required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Human MOV10 may regulate a wide range of RNA viruses and could also control the retrotransposition of endogenous retroelements in mammals(PMID:22727223). MOV10 has a broad antiretroviral activity that can target a wide range of retroviruses, and it could be actively involved in host defense against retroviral infection. MOV10 can potently inhibit HIV-1 replication at multiple stages(PMID:20215113). It is involved in the progression of telomerase-catalyzing reaction via the interaction of telomerase protein and telomere DNA.