验证数据展示
经过测试的应用
| Positive IHC detected in | human lung cancer tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
推荐稀释比
| Application | Dilution |
|---|---|
| Immunohistochemistry (IHC) | IHC : 1:20-1:200 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| KD/KO | See 1 publications below |
| IHC | See 2 publications below |
产品信息
14650-1-AP targets MPP3 in IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Applications | IHC, ELISA Application Description |
| Cited Applications | IHC |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | mouse |
| Immunogen | MPP3 fusion protein Ag6246 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| Synonyms | Discs large homolog 3, DLG3, MAGUK p55 subfamily member 3, MPP3, Protein MPP3 |
| Calculated Molecular Weight | 66 kDa |
| GenBank Accession Number | BC056865 |
| Gene Symbol | MPP3 |
| Gene ID (NCBI) | 4356 |
| RRID | AB_10949194 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q13368 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
MPP3, also named as DLG3, belongs to the MAGUK family which interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. MPP3 plays an important role in signal transduction.
实验方案
| Product Specific Protocols | |
|---|---|
| IHC protocol for MPP3 antibody 14650-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
J Neurosci PALS1 is essential for retinal pigment epithelium structure and neural retina stratification. | ||
J Neurosci MPP3 is required for maintenance of the apical junctional complex, neuronal migration, and stratification in the developing cortex.
|