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MS4A7 Polyclonal antibody

MS4A7 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 11864-1-AP

Print datasheet

Synonyms

4SPAN2, CD20 antigen like 4, CD20L4, CFFM4, MS4A7, MS4A8

验证数据展示

  • WB analysis using 11864-1-AP

    WB analysis using 11864-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 11864-1-AP (MS4A7 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inBV-2 cells, K-562 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

11864-1-AP targets MS4A7 in WB, ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human, mouse
Immunogen MS4A7 fusion protein Ag2442 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name membrane-spanning 4-domains, subfamily A, member 7
Synonyms 4SPAN2, CD20 antigen like 4, CD20L4, CFFM4, MS4A7, MS4A8
Calculated Molecular Weight 240 aa, 26 kDa
Observed Molecular Weight26 kDa
GenBank Accession NumberBC020673
Gene Symbol MS4A7
Gene ID (NCBI) 58475
RRIDAB_2144674
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9GZW8
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

The human MS4A family currently includes 18 members, and these proteins have four putative transmembrane domains (tetraspan) and several protein kinase C (PKC) phosphorylation sites. Membrane-spanning 4-domains a7 (MS4A7) is a member of the MS4A family. It is expressed by myeloid cells. MS4A7 can act as a NAM-specific pathogenic factor that exacerbates metabolic dysfunction-associated steatohepatitis (MASH) progression in mice (PMID: 38478630). There are two isoforms of MS4A7 protein, with molecular weights of 26.14 kDa and 21.41 kDa respectively.

实验方案

Product Specific Protocols
WB protocol for MS4A7 antibody 11864-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols