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- KD/KO Validated
MSRB2 Polyclonal antibody
MSRB2 Polyclonal Antibody for WB, IHC, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
WB, IHC, ELISA
Conjugate
Unconjugated
验证数据展示
经过测试的应用
| Positive WB detected in | mouse brain tissue, human heart tissue, mouse heart tissue, rat brain tissue |
| Positive IHC detected in | human kidney tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
推荐稀释比
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| Immunohistochemistry (IHC) | IHC : 1:100-1:400 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| KD/KO | See 1 publications below |
| WB | See 8 publications below |
产品信息
17629-1-AP targets MSRB2 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Applications | WB, IHC, ELISA Application Description |
| Cited Applications | WB |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse, rat |
| Immunogen | MSRB2 fusion protein Ag11881 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | methionine sulfoxide reductase B2 |
| Synonyms | CBS 1, CBS1, CGI 131, MSRB, MSRB2, PILB |
| Calculated Molecular Weight | 182 aa, 20 kDa |
| Observed Molecular Weight | 19 kDa |
| GenBank Accession Number | BC018030 |
| Gene Symbol | MSRB2 |
| Gene ID (NCBI) | 22921 |
| RRID | AB_2148380 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9Y3D2 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Methionine sulfoxide reductase B2(MSRB2), is a 182-amino acid protein with an N-terminal mitochondrial targeting signal, a catalytic cysteine, and 2 zinc-coordinating CxxC motifs. MSRB can catalyze the stereospecific reduction of methionine-R-sulfoxides to methionines. MSRB2 protects mitochondrial integrity and cell survival by scavenging reactive oxygen species.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for MSRB2 antibody 17629-1-AP | Download protocol |
| IHC protocol for MSRB2 antibody 17629-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Free Radic Biol Med Loss of methionine sulfoxide reductases increases resistance to oxidative stress. | ||
Front Pharmacol 3-Mercaptopyruvate Sulfurtransferase, Not Cystathionine β-Synthase Nor Cystathionine γ-Lyase, Mediates Hypoxia-Induced Migration of Vascular Endothelial Cells.
| ||
J Med Food Rice Protein Exerts Endogenous Antioxidant Capacity via Methionine Sulfoxide Reductase and the Nrf2 Antioxidant System Independent of Age. | ||
Food Sci Biotechnol Methionine strengthens anti-inflammation of rice protein via depressing NF-κB activation and stimulating Msr expression in rats fed cholesterol-enriched diets. | ||
J Food Biochem Rice protein stimulates endogenous antioxidant response attributed to methionine availability in growing rats. | ||
Mol Omics Rbm20 ablation is associated with changes in the expression of titin-interacting and metabolic proteins. |
