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Maralixibat Chloride

Maralixibat Chloride (LUM001 chloride) 是一种钠依赖性的胆汁酸转运抑制剂，可阻止胆汁酸在肠肝内的再循环

CAS号

228113-66-4

分子式

C40H56ClN3O4S

主要靶点

Potassium Channel

仅限科研使用

Cat No : CM09234

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Synonyms

SHP-625|SHP625|LUM001 chloride|Livmarli|Lopixibat chloride|SHP625 chloride|Lopixibat|SHP 625

验证数据展示

  • CAS No.: 228113-66-4

    Maralixibat Chloride
    CAS#: 228113-66-4

产品信息

Maralixibat Chloride, an apical, sodium-dependent, bile acid transport inhibitor, prevents enterohepatic bile acid recirculation.

CAS号 228113-66-4
分子式 C40H56ClN3O4S
主要靶点 Potassium Channel
主要通路 离子通道
分子量 710.41
纯度 98.54%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 SHP-625|SHP625|LUM001 chloride|Livmarli|Lopixibat chloride|SHP625 chloride|Lopixibat|SHP 625

靶点活性

Ileal sodium-dependent bile acid transporters:0.89 μM

体内活性

Maralixibat chloride can increase the level of sBA and reduce liver injury in cholestatic rats by partial bile duct ligation[1].

溶解度

DMSO:45.0 mg/mL (63.3 mM),ultrasonic and warming and heat to 60°C

参考文献

1.Kurata, Hitoshi; Bioorganic & Medicinal Chemistry Letters (2004), 14(5), 1183-1186

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
×
×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2