验证数据展示
发表文章中的应用
| WB | See 1 publications below |
产品信息
10003-0-Ig targets Marcksl1 in WB, ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | ELISA Application Description |
| 文献引用应用 | WB |
| 经测试反应性 | human, mouse |
| 文献引用反应性 | rat |
| 免疫原 | Recombinant Protein 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | MARCKS-like 1 |
| 别名 | AL022768, AW215397, AW536807, D4Bc1, F52, MacMARCKS, Macs 2, Macs 3, Macs2, Macs3, MARCKS like 1, Marcksl1, Mlp, Mrp |
| 计算分子量 | 40 kDa |
| GenBank蛋白编号 | BC006757 |
| 基因名称 | Marcksl1 |
| Gene ID (NCBI) | 17357 |
| RRID | AB_2297361 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P28667 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
MacMARCKS is a member of MARCKS family of PKC substrate. It is widely used in the signal transduction studies as an indictor of PKC activation. The protein has a calculated molecular weight of 20 kDa and an apparent molecular weight of 42-45 kDa in different species on SDS PAGE. MacMARCKS functions in many aspects of cell physiology including integrin activation, cell spreading and phagocytosis. Its functions are though to associate with its ability in binding and regulating actin and microtubule cytoskeleton. Current evidence indicated that this protein also involved controls membrane fluidity and molecular mobility of membrane proteins