验证数据展示
产品信息
60348-1-PBS targets Melan-A in IHC, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | IHC, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | Melan-A fusion protein Ag13387 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | melan-A |
别名 | Antigen LB39 AA, Antigen SK29 AA, MART 1, MART1, melan A, Melan-A , MLANA, Protein Melan A |
计算分子量 | 13 kDa |
GenBank蛋白编号 | BC014423 |
基因名称 | MelanA |
Gene ID (NCBI) | 2315 |
RRID | AB_2881457 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q16655 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Melan-A is a melanocyte differentiation antigen, recognized by autologous cytotoxic T lymphocytes. Melan-A is also called MART-1 (melanoma antigen recognized by T cells). The Melan-A/MART-1 gene encodes this protein, 20-22 kDa, associated with endoplasmic reticulum and melanosomes. The function of the protein is unknown. Melan-A, isolated as a melanoma-specific antigen, is a transmembrane protein, which is expressed in skin, retina and the majority of cultured melanocytes as well as in melanomas. Melan A is expressed in more than 85% of melanomas.