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Mouse Mmp9 Recombinant antibody, PBS Only

Mmp9 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

230069G7

Cat no : 82854-8-PBS

Print datasheet

Synonyms

MMP 9, matrix metallopeptidase 9, Clg4b, B/MMP9, AW743869

验证数据展示

  • WB analysis using 82854-8-RR (same clone as 82854-8-PBS)

    WB analysis using 82854-8-RR (same clone as 82854-8-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82854-8-RR (Mmp9 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82854-8-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 82854-8-RR

    Affinity and Kinetic Characterization of 82854-8-RR

    Biolayer interferometry (BLl) kinetic assays of 82854-8-RR against Mouse Mmp9 were performed. The affinity constant is 1.38 nM.

产品信息

82854-8-PBS targets Mmp9 in WB, Indirect ELISA applications and shows reactivity with mouse samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity mouse
Immunogen Recombinant protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name matrix metallopeptidase 9
Synonyms MMP 9, matrix metallopeptidase 9, Clg4b, B/MMP9, AW743869
Calculated Molecular Weight81kd
Observed Molecular Weight100 kDa
GenBank Accession NumberNM_013599
Gene Symbol Mmp9
Gene ID (NCBI) 17395
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP41245-1
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Mmp9 (matrix metallopeptidase 9), also known as Clg4b. It is expected to be located inextracellular matrix. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes, such as arthritis or metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. Studies in rhesus monkeys suggest that MMP9 is involved in IL-8-induced mobilization hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. The pro-MMP9 is 92 kDa, and it can be detected a processed form of 68 kDa. This protein can exist as a dimer of 180 kDa (PMID:7492685).