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Recombinant Mouse CD79B protein (rFc Tag)

种属

Mouse

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg2113

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Synonyms

B-cell antigen receptor complex-associated protein beta chain, B-cell-specific glycoprotein B29, Igb, Ig-beta, Immunoglobulin-associated B29 protein

验证数据展示

  • Purity of Recombinant Mouse CD79B was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) conditions and stained using Coomassie blue.

    Purity of Recombinant Mouse CD79B was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Mouse CD79B protein Val26-Asp158 (Accession# P15530) with a rabbit IgG Fc tag at the C-terminus.
基因ID 15985
蛋白编号 P15530
预测分子量 41.4 kDa
SDS-PAGE 47-60 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

CD79 molecule encompasses two transmembrane proteins, CD79a and CD79b, which form a disulfide-linked heterodimer and are members of the immunoglobulin (Ig) gene superfamily. CD79b molecule (also known as B29, IGB, AGM6, and Igbeta) is expressed almost exclusively on B cells and B-cell neoplasms, influencing antigen internalization and increasing antigen presentation efficiency. CD79b mutation could be a key biomarker for DLBCL disease progression.

参考文献:

1. C J van Noesel, et al. (1991). J Immunol. Jun 1;146(11):3881-8.
2. C J Van Noesel, et al. (1992). J Exp Med. Jun 1;175(6):1511-9.
3. J Hombach, et al. (1990). Nature. Feb 22;343(6260):760-2.
4. C Bonnerot, et al. (1995). Immunity. Sep;3(3):335-47.
5. Peng-Peng Xu, et al. (2022). Clin Lymphoma Myeloma Leuk. Dec;22(12):e1051-e1058.e1.